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Using two separate drugs to lose weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err along the side of caution and let the FDA do its job and demand some investigation be done so the public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications. Researchers found out that participants using this drug for a year, lost weight within four weeks and have kept the body weight off through the entire 56 weeks in the study. Contrave can be a combination with the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more efficient and safer. Combo-pilling may be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular may be the fact that as of right now there aren't any long term prescription slimming capsules that have been approved by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug also can raise blood pressure and pulse rate, and really should not be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must stop used in patients with uncontrolled high hypertension, and also by a person with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients for the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. Acamprosate also activly works to eliminate the wish to drink by reducing the the cravings for alcohol consumption. The major difference between Naltrexone and Acamprosate is the fact that Acamprosate just isn't yet accessible in the United States. While it may be widely studied in Europe the precise chemical reason that it works remains unknown. It is thought that it inhibits receptors in the brain which process glutamate, which in effect alters the way ones body reacts to alcohol intake. Several of the European research has revealed a lot of promise with Acamprosate for the reason that some of the patients had an almost double success rate for staying sober.