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Using two separate drugs to lose weight naturally can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you ought to err on the side of caution and allow FDA do its job and demand some study be done so the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on their medications. Researchers found that participants using this drug for any year, dropped a few pounds within 4 weeks and have kept the body weight off through the entire 56 weeks with the study. Contrave is really a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, that might make them more potent and safer. Combo-pilling could be the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that by right now there are not any long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug may also raise blood pressure level and heart rate, and mustn't be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure, and also by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. 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